Bartter's,Gitelman's and Liddle's Syndrome

 ***Bartter's,Gitelman's and Liddle's Syndrome***

* Generally Features of Bartter's Syndrome is as Feature of Loop Dieuretics use  and features of  Gitelman's Syndrome is as Features of  Thiazide Diuretics use.

* Blood Pressure: In Liddle's Syndrome there is High blood pressure But in Gitelman's Syndrome Blood pressure remains normal and in Bartter's Blood pressure may be normal or low in comparison to general population.

* Age: Liddle's Syndrome  affect generally in Childhood, Bartter's syndrome in infancy in early adulthood Gitelman's Syndrome.

*Potassium: In each three condition there is hypokslemia.But there is mild hypokalemia in Liddle's Syndrome and in Gitelman's Syndrome hypokalemia ranges from 2-3 mmol/L and may be asymptomatic.

*Alkalosis: Mild metabolic Alkalosis in all three

*Magnesium: In Liddle's level of  Magnesium in blood is normal,In Gitelman it usually decreased but Bartter it may low or normal.

*Aldosterone and Renin: In Liddle's Aldosterone and Renin decreases but in other two opposite occurs. 

*Urinary Prostaglandin E2: It is increased only Bartter's Syndrome but in other two it is ok.